ProThermDB: thermodynamic database for proteins and mutants revisited after 15 years
نویسندگان
چکیده
منابع مشابه
ProTherm: Thermodynamic Database for Proteins and Mutants
The first release of the Thermodynamic Database for Proteins and Mutants (ProTherm) contains more than 3300 data of several thermodynamic parameters for wild type and mutant proteins. Each entry includes numerical data for unfolding Gibbs free energy change, enthalpy change, heat capacity change, transition temperature, activity etc., which are important for understanding the mechanism of prote...
متن کاملRecent Developments of ProTherm: Thermodynamic Database for Proteins and Mutants
Thermodynamic data for proteins are important for understanding the mechanism of protein folding and stability. In recent years, the accumulation of thermodynamic data has been steadily increasing. Pfeil [4] collected a set of thermodynamic data on protein folding and stability from experimental studies that have been published until 1996. Recently, we have developed an electronically accessibl...
متن کاملRecent Developments in ProTherm: Thermodynamic Database for Proteins and Mutants
Due to the rapid progress in genome analysis, complete genome sequences of many organisms become available. Now proteins are the next target for intensive study, as evidenced by the emerging fields such as structural genomics and proteome analysis. In order to elucidate molecular function of proteins, we need to have knowledge of their amino acid sequence and structure. The sequence and structu...
متن کاملCurrent Status of ProTherm: Thermodynamic Database for Proteins and Mutants
M. Michael Gromiha1 Hatsuho Uedaira1 [email protected] [email protected] Jianghong An2 Samuel Selvaraj1 [email protected] [email protected] Ponraj Prabakaran1 Akinori Sarai1 [email protected] [email protected] 1 RIKEN Tsukuba Institute, Institute of Physical and Chemical Research, 3-1-1 Koyadai,Tsukuba, Ibaraki 305-0074, Japan 2 Scripps Research Institute, La Jolla...
متن کاملProTherm, version 2.0: thermodynamic database for proteins and mutants
ProTherm 2.0 is the second release of the Thermo-dynamic Database for Proteins and Mutants that includes numerical data for several thermodynamic parameters, structural information, experimental methods and conditions, functional and literature information. The present release contains >5500 entries, an approximately 67% increase over the previous version. In addition, we have included informat...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2020
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkaa1035